Report from the Dogwood Center


The injection-related AIDS epidemic in the United States:
States and metro areas with the highest rates 

November 1999

Dawn Day, PhD

Contents:

Overview   

States where the injection-related AIDS epidemic is most severe  

Metropolitan areas where the injection-related AIDS epidemic is most severe  

The crisis among African Americans and Latinos  

The epidemic's trend: growing numbers living with injection-related AIDS  

Increasing heroin use  

Effective prevention includes access to sterile needles  

The low cost of clean-needle programs  

Overview
At least half of all new HIV cases now involve people who inject drugs or their heterosexual partners.(1)  This report identifies the states and metropolitan areas where the injection-related part of AIDS epidemic is most concentrated and highlights the severe impact of the epidemic on African Americans and Latinos. 

Two trends increase the likelihood of HIV spreading through the sharing of syringes in the absence of clean needle programs.  First, the price of heroin has fallen and purity increased.  Second, medical advances in AIDS treatment have resulted in an increase in life expectancy for persons who inject drugs and who are already infected with HIV/AIDS.

Six major, federally funded studies have found needle exchange programs are effective in slowing the spread of HIV and do not increase drug use.

Major medical associations in the United States, including the American Medical Association, have called for federal funding of needle exchange programs and, at the state level, the elimination of barriers to sterile needles.

HIV prevention is cost effective. Pharmacy sale of syringes costs taxpayers nothing.  Preventing new HIV infections through a needle exchange program is much less costly than treating a patient with HIV/AIDS, where the annual cost of prescription medicine can run as high as $17,000 a year.

States where the injection-related AIDS epidemic is most severe

In 1998, New York State led the nation with the highest rate of AIDS spread through injecting drug use.  Maryland, Delaware, Connecticut, and New Jersey round out the top five. (See Figure 1 and Attachment 1.)  

Figure 1.  States with the highest rates of injection-related AIDS, 1998

Rank in 1998

       State

Rate per million

1

 

 

     New York

314

 

2

 

 

     Maryland

252

 

3

 

 

     Delaware

227

 

4

 

 

     Connecticut

205

 

5

 

 

     New Jersey

198

 

6

 

 

     Louisiana

106

 

7

 

 

     Pennsylvania

102

 

8

 

 

     Florida

100

 

*9

 

 

     Massachusetts

98

 

*9

 

 

     Rhode Island    

98

 

*

 

 

     Tie with another state

 

 

Metropolitan areas where the injection-related AIDS epidemic is most severe

Among metropolitan areas of over 500,000, New York City, in 1998, had the highest rate of AIDS spread through injection drug use, followed by the Baltimore metro area in Maryland, the Jersey City and Newark metro areas of New Jersey and the Wilmington metro area in Delaware.  (See Figure 2 and Attachment 2.)

 

Figure 2. U.S. Metropolitan areas of 500,000 or more with the highest rates of injection-related AIDS, 1998

Rank in 1998

Metro areas of 500,000 or more

Rate per million

 

1

 

 

New York, NY

435

 

2

 

 

Baltimore, MD

343

 

3

 

 

Jersey City, NJ

320

 

4

 

 

Newark, NJ

280

 

5

 

 

Wilmington, DE

213

 

*6

 

 

Baton Rouge, LA

207

 

*6

 

 

Hartford, CT

207

 

8

 

 

West Palm Beach, FL

191

 

9

 

 

San Francisco, CA

189

 

10

 

 

New Haven, CT

171

 

11

 

 

Philadelphia, PA

150

 

12

 

 

Washington, DC

143

 

13

 

 

Springfield, MA

140

 

14

 

 

Bergen-Passaic, NJ

127

 

15

 

 

New Orleans, LA

114

 

16

 

 

Houston, TX

104

 

*17

 

 

Miami, FL

97

 

*17

 

 

Orlando, FL

97

 

19

 

 

Rochester, NY

96

 

20

 

 

Atlanta, GA

94

 

 

 

 

San Juan, PR

367

 

*

Tie with another metro area

The comparison for both states and metropolitan areas is on the rate of new injection-related AIDS cases in 1998 per million population, using a special tabulation from the Centers for Disease Control and Prevention (CDC).  

The rates, based on new AIDS cases in their respective states and metropolitan areas, are the result of two factors.  The number of new drug-related HIV infections in the area 8 or 10 years previously (in the absence of treatment, the typical interval between initial infection and the development of AIDS) and the extent to which persons with injection-related AIDS have been able to gain access to the life-saving antiretroviral therapies.

Although not a perfect measure, the rankings do permit us to identify those states and metropolitan areas where the drug-related HIV/AIDS epidemic is most severe.  And where greater efforts need to be made in prevention.

The crisis among African Americans and Latinos

The injection-related AIDS epidemic has been particularly severe among African Americans and Latinos.  From the beginning of the epidemic through the end of 1998, African Americans and Latinos together accounted for three quarters of all injection-related AIDS cases! 

In 1998, the rate of injection-related AIDS cases among blacks in the United States was 14 times higher than the rate for whites.  The rate for Latinos was 6 times higher than the rate for whites. (2)

The epidemic's trend: growing numbers living with injection-related AIDS

The decline in AIDS deaths and the remarkable success of antiretroviral therapy in helping people infected with HIV maintain their health has led some to believe HIV prevention is less important than it once was. 

That is not the case.  As antiretroviral therapy has prevented, or at least delayed, the onset of full-blown AIDS among many individuals with HIV and with AIDS deaths declining, there are growing numbers of persons living with injection-related AIDS. (3)  With increasing numbers of persons living with HIV and AIDS, there is an ever growing need for effective prevention.

Information on HIV infections is incomplete for a variety of reasons, but we can get some sense of the expanding nature of the epidemic by looking at the trend in injection-related AIDS.  (See Figure 3 and Attachment 3.)  

Based on CDC data, Figure 3 shows how the number of persons living with injection-related AIDS has grown, doubling between 1992 and 1998.

By the end of 1998, 102,000 people were living with injection-related AIDS (not HIV) in the United States.  If we could add in cases of injection-related HIV, the number of people living with the virus spread through infected needles would be even higher. (4)

Now more U.S. residents are living with injection-related HIV/AIDS than ever before. 

Increasing heroin use

In recent years, there has been an increase in heroin use, the drug most commonly injected.

According to the Office of National Drug Control Policy, heroin use has increased as the price of heroin has fallen and availability increased. (5) 

Because of the purity, new users often smoke or sniff heroin, rather than inject it.  However there is the danger that, when money is short, new users will shift to injecting, which requires less heroin to produce a high.

With increases both in the number of persons are living with injection-related HIV/AIDS and the number of heroin users, the need for effective HIV prevention is also growing.

Effective prevention includes access to sterile needles

Drug education, drug treatment, and condom distribution (to potential partners of injecting drug users) are important, but not enough by themselves to eliminate the spread of HIV through infected needles.

Improved access to sterile needles is needed.  This can be done through pharmacy sales of syringes and needle exchange programs.  Needle exchange programs permit injecting drug users to exchange used needles for sterile ones.

Federally funded reports from eight major scientific bodies, including the National Research Council and Institute of Medicine have all recommended the use of needle exchange programs as part of an effective HIV/AIDS prevention strategy. The reports are unanimous in concluding that needle exchange programs slow the spread of HIV and do not increase drug use. (6)  

Needle exchange programs have been shown to reduce the spread of HIV by at least a third. (7) 

While publicly acknowledging the validity of the scientific research supporting the effectiveness of needle exchange programs, Secretary of Health and Human Services Donna E. Shalala has not released federal HIV prevention funds for use in needle exchange programs. (8)

Recently the American Medical Association, the American Pharmaceutical Association, the Association of State and Territorial Health Officials, the National Association of Boards of Pharmacy and the National Alliance of State and Territorial AIDS Directors issued a joint letter encouraging state-level action to reduce the legal and regulatory barriers that currently restrict access to sterile syringes in nearly every state. (9)  These organizations earlier had stated their support for federal funding for needle exchange programs.

The states have been very slow to respond to the need for AIDS prevention through increased access to sterile needles.  Of the ten states with the highest rates of injection-related AIDS, four (Delaware, Florida, Louisiana, and New Jersey) have laws that prevent the establishment of needle exchange programs. (10)

New York, Maryland, Connecticut, Pennsylvania, Rhode Island and Massachusetts permit injecting drug users access to sterile needles under some conditions, but even with these states, the situation is mixed.  Maryland, for example, permits needle exchange only in Baltimore City.  In Pennsylvania, needle exchanges exist only on the basis of local initiative.  In Massachusetts, the Springfield metro area, which ranks 13th in the nation with regard to injection-related AIDS, has no needle exchange program.  

New York, which leads the nation, has historically had a high concentration of heroin users.  Needle exchange programs in New York City have resulted in a reduction of the per capita HIV rate. (11)  However the number of needle exchange programs are still inadequate to meet the need.  And pharmacy sales of syringes are restricted throughout the state.

The low cost of clean-needle programs

Needle exchange programs not only save lives, they also save money.  Preventing the spread of HIV through needle exchange costs much less than treating HIV/AIDS after a person is infected. 

Using sophisticated mathematical models, a University of California team of investigators estimates that, over a five-year period, it costs between $4,000 and $12,000 in needle-exchange program expenses for each HIV infection averted. (12)  The cost of medicine for antiretroviral therapy for that same five-year period would be more than $60,000.  One recent estimate puts the cost of antiretroviral therapy at over $17,000 for a single year! (13)  If we had the data to add in doctors' fees and hospitalization, the cost difference between prevention through needle exchange and treatment would be even greater.

Attachment 1. Background information for Figure 1

Injection-related AIDS cases include persons who inject drugs and the heterosexual partners of persons who inject drugs.  Rates were calculated by averaging injection-related AIDS cases among persons age 13 and older for the 3-year period 1996-1998 and then dividing by persons age 13 and over in 1997.  The states were then ranked by rate.  When ties occurred, the states involved were given the same rank.

The data are from a special tabulation from the Centers for Disease Control and Prevention.

Attachment 2.  Background information for Figure 2

Data are from the same special CDC tabulation as described in Attachment 1.  Rates were calculated by averaging injection-related AIDS cases among persons age 13 and older for the 3-year period 1996-1998 and then dividing by the total population in 1997.

The metro areas were then ranked by rate.  When ties occurred, the metro areas involved were given the same rank.

Attachment 3.  Background information for Figure 3

Injection-related AIDS cases here refers only to persons who inject drugs and NOT their sexual partners.  Since AIDS spread through heterosexual sex has been one of the most rapidly increasing risk groups, Figure 3, by excluding that group, understates the growth of the epidemic. 

The data are from CDC, HIV/AIDS Surveillance Report. U.S. HIV and AIDS cases reported through June 1999.  Vol. 11, no. 1. Tables 25 and 28.


Footnotes

(1)  Scott D. Holmberg. "The Estimated Prevalence and Incidence of HIV in 96 Large US Metropolitan Areas."  American Journal of Public Health.  May 1996. p.642.  

(2)  Data are from the same special CDC tabulation as described in Attachment 1.  Rates are calculated in the same way as in Attachment 1.

(3)  The number of persons living with AIDS is not available at the state or metro area level; the only information available at the state and metro area level is the number of new AIDS cases.  Estimates of persons living with AIDS in the U.S. are from the HIV/AIDS Surveillance Reports of the Centers for Disease Control and Prevention.  The 1992 figures are from the 12/1998 report, Table 27 and the 1993-1998 figures are from the 6/99 report, Table 25.

(4)  The CDC reported an additional 22,000 persons living with injection-related HIV (not AIDS) from 33 states in 1998.  But this number seriously understates the number of persons living with injection-related HIV, since several states where the epidemic is severe do not report on the number of persons living with injection-related HIV and, in any case, many persons with HIV do not themselves know they are infected.  CDC. HIV/AIDS Surveillance Report.  U.S. HIV and AIDS cases reported through  December 31, 1998, vol. 10, no. 2. Table 6.

(5)  In 1998 the average retail price for a pure gram of heroin was approximately $1,799, significantly lower than in 1981 when the retail price per gram was estimated to be $3,115. The average purity for retail heroin in 1998 was 25 percent, much higher than the average of 19 percent reported a decade ago.  Office of National Drug Control Policy.  National Drug Control Strategy 1999. Washington, D.C. 1999. p. 30f.

(6)  The studies are:

  • National Commission on AIDS, The Twin Epidemics of Substance Use and HIV, Washington, DC. 1991.

  • General Accounting Office, Needle Exchange Programs: Research Suggests Promise as an AIDS Prevention Strategy, Report Number GAO/HRD-93-60, Washington, DC: US GPO, 1993.

  • University of California, The Public Health Impact of Needle Exchange Programs in the United States and Abroad. Summary, vols. I and II.  Peter Lurie, Arthur L. Reingold, et al., San Francisco: University of California, 1993; available from the National AIDS Clearinghouse, PO Box 6003, Rockville, MD 20848-6003.

  • National Research Council and Institute of Medicine, Jacques Normand, David Vlahov, and Lincoln E. Moses, eds., Preventing HIV Transmission: the Role of Sterile Needles and Bleach.  Washington, DC: National Academy Press, 1995.

  • Office of Technology Assessment of the US Congress. The Effectiveness of AIDS Prevention Efforts, 1995,  PB96107529.  Springfield, VA: National Technical Information Service.

  • National Institutes of Health Consensus Panel, Interventions to Prevent HIV Risk Behaviors, 1997,  Kensington, MD: NIH Consensus Program Information Center.   

(7) Robert Heimer, Kaveh Khoshnood, P. Clay Stephens, and others. "Evaluating a needle exchange programme." International Journal of Drug Policy. Vol. 7, no. 2. 1996. pp. 123-129.  Later work from many authors confirms the effectiveness of needle exchange programs.  See especially Robert Heimer, Keveh Khoshnood, Dan Bigg, Joseph Guydish and Benjamin Junge, "Syringe use and reuse: effects of syringe exchange programs in four cities," Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology. vol. 18. Supplement 1. July 1998. pp. s37-s44.

(8)  "U.S. won't fund needle exchanges." Associated Press. April 20, 1998.

(9)  American Medical Association, American Pharmaceutical Association, Association of State and Territorial Health Officials, National Association of Boards of Pharmacy, and National Alliance of State and Territorial AIDS Directors. "HIV Prevention & Access to Sterile Syringes." Letter to colleagues.  October 1999.

(10)  Since needle exchange programs reach out to drug users, helping them to get into both drug treatment and HIV treatment, if needed, areas with needle exchanges have a more accurate count of the number of persons infected than do areas where there is no needle exchange program.

(11)  Don C. Des Jarlais, Theresa Perils, Samuel R. Friedman, et al, "Declining Seroprevalence in a Very Large HIV Epidemic: Injecting Drug Users in New York City, 1991 to 1996," American Journal of Public Health, 1998. vol. 88. p.1801-06.

(12)  National Research Council and Institute of Medicine,  Jacques Normand, David Vlahov, and Lincoln E. Moses, eds.,  Preventing HIV Transmission: The Role of Sterile Needles and Bleach.  Washington, DC:  National Academy Press, 1995, pp. 86-88.

(13)  A recent study by Caro Research, an independent consulting firm in Massachusetts, showed that highly active antiretroviral therapy, using 3 to 4 drugs costs $17,600 a year.  Reuters. "It costs $17,600 a year to treat HIV in U.S.-study." September 27, 1999.

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